Tag Archives: cell_development

Telomerase Replication

Telomerase, , , , , , , , ,

[mage lang=”en|es|fr|en” source=”flickr”]telomerase replication[/mage]
HELP multiple choice?

The enzyme telomerase solves the problem of replication at the ends of linear chromosomes by which method?

A)adding a single 5′ cap structure that resists degradation by nucleases
B)adding numerous GC pairs which resist hydrolysis and maintain chromosome integrity
C)adding numerous short DNA sequences such as TTAGGG, which form a hairpin turn
D)causing specific double strand DNA breaks that result in blunt ends on both strands

C

Telomere Replication Made Easy

Telomerase Dna Replication

Telomerase, , , , , ,

[mage lang=”en|es|fr|en” source=”flickr”]telomerase dna replication[/mage]
DNA replication question?

how does shortening of the telomeres(leading to unstable chromosomes which will result in the cell line dying) occurs if the telomeric loss can be compensated by the enzyme telomerase?

That’s a good question.

In yeast, protozoa and other single-celled organisms, telomerase is active. These cells can divide forever. However, in most cells of higher organisms, telomerase is inactive and the ends of the chromosomes get shorter with each cell division. At a certain telomeric length, the cells no longer divide.

However, if telomerase becomes active, and the ends of the chromosomes lengthen, a signal is conveyed for cells to keep dividing, which can lead to cancerous growth.

Hope that helps.