Tag Archives: telomere

Telomere Telomerase And Cancer

[mage lang=”en|es|fr|en” source=”flickr”]telomere telomerase and cancer[/mage]
If telomere shortening could be avoided (eg, telomerase), what do you think the benefits and risks would be?

Do you think cell senescence or slow or stop the aging increased cancer mechanical, such as longer life cells encourage such developments. Do you think you that any significant changes would occur?

A variety of syndromes of accelerated aging are associated with short telomeres. These include Werner syndrome syndrome, ataxia telangiectasia, Bloom, Fanconi anemia, Nijmegen breakage syndrome and ataxia telangiectasia, a disorder. The genes that are mutated in these diseases have a role in the repair of damage to DNA, and their precise roles in maintaining telomere length is an active area of ​​research. While it is unknown extent of erosion telomeres contributes to the normal aging process, maintenance of DNA, in general, and specifically to telomeric DNA, have emerged as key players. Dr. Michael Fossel has been suggested that telomerase therapy (see link) can be used not only to fight cancer, but to really get on aging and prolonging human life significantly. He believes that human trials of telomerase therapies based on extending the life occur in the next 10 years. This chronology is important because it coincides with the retirement of baby boomers United States and Europe. When cells are approaching the Hayflick limit in cell culture, the aging time can be extended by inactivation the tumor suppressor protein – TP53 and retinoblastoma protein (pRb). Cells that have been modified so eventually undergo an event called a "crisis" when the majority of cells in culture die. Sometimes a cell will stop dividing once they reach the crisis. Normally, the telomeres are lost, and the integrity of chromosomes is reduced at each subsequent cell division. Chromosome ends are exposed interpreted as a double-strand breaks (DSB) of DNA, this damage is usually repaired by reconnecting (religation) the broken ends together. When the cell is due to telomeres shortened, the ends of chromosomes may be set. This temporarily solves the problem of lack of telomeres, but during the anaphase of cell division the chromosomes fused randomly broken causing many mutations and chromosomal abnormalities. As this process continues, the genome of the cell becomes unstable. Over time, if enough damage will occur in the chromosomes of the cell so the cell dies (for programmed cell death (apoptosis or not), or an additional mutation with activities of telomerase.

Telomerase.org Intro: andrew@andrewstraw.com

Telomerase Levels

[mage lang=”en|es|fr|en” source=”flickr”]telomerase levels[/mage]
Which would most dramatically impact the levels of free radicals in one’s body?

a.consuming antioxidants like vitamin E
b.getting an injection of telomerase
c.contracting sickle cell anemia
d.engaging in aerobic exercise

i think,and according to book
consuming antioxidants like vitamin E

The free radical theory of aging implies that antioxidants such as Vitamin A, vitamin C, vitamin E, and Superoxide dismutase will slow the process of aging by preventing free radicals from oxidizing sensitive biological molecules or reducing the formation of free radicals. The antioxidant chemicals found in many foods are frequently cited as the basis of claims for the benefits of a high intake of vegetables and fruits in the diet.

Nonetheless, some recent studies tend to show that antioxidant therapy have no effect and can even increase mortality [18][19][20][21][22][23]. Proponents of the theory claim that this phenomenon can be explained by hormesis: The addition of antioxidants can lead to a decrease of normal biological response to free radicals and lead to a more sensitive environment to oxidation

Immortal – Maintaining human telomerase levels

Telomerase Treatments

[mage lang=”en|es|fr|en” source=”flickr”]telomerase treatments[/mage]
Bio Question?! Please HELP!?

Biology Questions…?
1. State the relationship between the presence of telomerase, telomere length, and the number of cell divisions.

2. Explain how the knowledge of telomerase may lead to an effective treatment for cancer.

3. State one way telomerase could be used to treat patients who have HIV.

4. Compared to small cells, large cells have more trouble
A. dividing
B. producing daughter cells
C. moving needed materials in and waste products out
D. making copies of their DNA

#4 = definetely not A
Thanks!!! but I still need 1, 2 and 3. It is urgent!!! so please help

These are exact questions on a lab I did. lol.

2. knowing how to stop telomerase from being secreted would stop the lengthening of telomeres on cancer cells.

4. I believe is D.

3. You could use telomerase to help lengthen the telomeres to keep producing the nessecary blood cells.

Ever Youth Medicine In Research Process Part 2