The electron transport chain is great at producing ATPs very efficently. There is a cost. Production of Peroxides and Superoxides which are very reactive free radicals that cause damage and aging of the mitochondria. What research is/ has been conducted to combat this problem. Is anything in development that could seriously extend the lives of ever member of the human race? If something could keep ATP production optimal without minimal production of the free radicals. We’d live a long time. Oh yeah.. keep telomerase from shedding the telomeres of the DNA alpha helices.
The peroxides and superperoxides are not free radicals but do decompose to give free radicals. The actions of free radicals is well known to be inhibited by various antioxidants such as anthocyanin pigments or even vitamin C or vitamin E.
The telomers are another story.