[mage lang=”en|es|fr|en” source=”flickr”]telomerase rna primer[/mage]
what exactly happens after telomerase is used?
I know that it is an enzyme that has a short molecule of RNA with a sequence that serves as a template for extending the 3′ end of the telomere. But I see that after the primer is removed from 5′ it is still shorter than the other strand 3′. this is what it says in teh book”After the primer is removed, the result is a longer telomere with a 3′ -end “overhang (LM).” So what this mean?
Telomerase is an enzyme that adds specific DNA sequence repeats (“TTAGGG” in all vertebrates) to the 3′ (“three prime”) end of DNA strands in the telomere regions, which are found at the ends of eukaryotic chromosomes. The telomeres contain condensed DNA material, giving stability to the chromosomes. The enzyme is a reverse transcriptase that carries its own RNA molecule, which is used as a template when it elongates telomeres, which are shortened after each replication cycle. Telomerase was discovered by Carol W. Greider in 1984.