Tag Archives: telomerase sequence specific

Telomerase Sequence

[mage lang=”en|es|fr|en” source=”flickr”]telomerase sequence[/mage]
Enzyme telomerase question.?

Tetrahymena contains the enzyme Telomerase. A mutant tetrahymena was isolated that had an altered sequence in its telomeric DNA. What change in the the telomerase enzyme would have caused this phenotype? Any help on this would be greatly appreciated! Thanks.

I guessing that it has to do with a change in the “TERT” subunit of the enzyme.
http://en.wikipedia.org/wiki/Telomerase#Structure
http://en.wikipedia.org/wiki/Telomerase_Reverse_Transcriptase